6-ethyl-5-[3-(3,4,5-trimethoxyphenyl)prop-1-yn-1-yl]pyrimidine-2,4-diamine
Q81R22 — Dihydrofolate reductase
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand EKB
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand EKB
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| Q81R22 | n/a | 3jvx | EKB | A | 208 | e3jvxA1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q81R22 | n/a | 3jvx | EKB | B | 208 | e3jvxB1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q81R22 | n/a | 3jwc | EKB | A | 208 | e3jwcA1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q81R22 | n/a | 3jwc | EKB | B | 208 | e3jwcB1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |