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Attributes

UniProt ID
Q81R22
Protein Name
Dihydrofolate reductase
Ligand Name
TRIMETHOPRIM
DrugBank ID
DB00440
PDB Ligand Accession
TOP
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
IEDVJHCEMCRBQM-UHFFFAOYSA-N
SMILES
COc1cc(cc(c1OC)OC)Cc2cnc(nc2N)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 3FL9
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Color Legend
Unassigned regionsLigand / hetero atomse3fl9A1e3fl9B1e3fl9C1e3fl9D1e3fl9E1e3fl9F1e3fl9G1e3fl9H1
ECOD domains from experimental PDB structures interacting with ligand DB00440
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q81R22DB00440TOP3fl9e3fl9A1A:1-166
Q81R22DB00440TOP3fl9e3fl9B1B:1-162
Q81R22DB00440TOP3fl9e3fl9C1C:1-166
Q81R22DB00440TOP3fl9e3fl9D1D:1-166
Q81R22DB00440TOP3fl9e3fl9E1E:1-166
Q81R22DB00440TOP3fl9e3fl9F1F:1-166
Q81R22DB00440TOP3fl9e3fl9G1G:1-166
Q81R22DB00440TOP3fl9e3fl9H1H:1-166
Q81R22DB00440TOP3jw3e3jw3A1A:-2-162
Q81R22DB00440TOP3jw3e3jw3B1B:-2-162
Q81R22DB00440TOP3jw5e3jw5A1A:-2-162
Q81R22DB00440TOP3jw5e3jw5B1B:-2-162