DrugDomain logoDrugDomain

4-[4-[(4,4-dimethylpiperidin-1-yl)methyl]phenyl]-1-methyl-9-[6-(methylamino)pyrimidin-4-yl]-1,4,9-triazaspiro[5.5]undecan-2-one

Q86U44 — N-adenosine-methyltransferase catalytic subunit METTL3 -adenosine-methyltransferase 70 kDa subunit

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand UZ2

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand UZ2

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q86U44n/a7o2hUZ2A601e7o2hA1Rossmann-likeRossmann-relatedS-adenosyl-L-methionine-dependent methyltransferasesMT-A70