methyl 2-[2-{2-chloro-5-[(2R)-2-hydroxy-3-(methylamino)propoxy]phenyl}-6-(3,5-dimethyl-1,2-oxazol-4-yl)-5-methylpyrimidin-4-yl]-2,7-diazaspiro[3.5]nonane-7-carboxylate

Q86X55 — Histone-arginine methyltransferase CARM1

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand BW4

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand BW4

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q86X55	n/a	6arj	BW4	A	502	e6arjA1	Rossmann-like	Rossmann-related	S-adenosyl-L-methionine-dependent methyltransferases	PrmA
Q86X55	n/a	6arj	BW4	A	502	e6arjA2	Arginine methyltransferase oligomerization subdomain	Arginine methyltransferase oligomerization subdomain	Arginine methyltransferase oligomerization subdomain	PRMT_C
Q86X55	n/a	6arj	BW4	A	502	e6arjB1	Arginine methyltransferase oligomerization subdomain	Arginine methyltransferase oligomerization subdomain	Arginine methyltransferase oligomerization subdomain	PRMT_C
Q86X55	n/a	6arj	BW4	B	502	e6arjA2	Arginine methyltransferase oligomerization subdomain	Arginine methyltransferase oligomerization subdomain	Arginine methyltransferase oligomerization subdomain	PRMT_C
Q86X55	n/a	6arj	BW4	B	502	e6arjB1	Arginine methyltransferase oligomerization subdomain	Arginine methyltransferase oligomerization subdomain	Arginine methyltransferase oligomerization subdomain	PRMT_C
Q86X55	n/a	6arj	BW4	B	502	e6arjB2	Rossmann-like	Rossmann-related	S-adenosyl-L-methionine-dependent methyltransferases	PrmA
Q86X55	n/a	6arj	BW4	C	502	e6arjC1	Arginine methyltransferase oligomerization subdomain	Arginine methyltransferase oligomerization subdomain	Arginine methyltransferase oligomerization subdomain	PRMT_C
Q86X55	n/a	6arj	BW4	C	502	e6arjC2	Rossmann-like	Rossmann-related	S-adenosyl-L-methionine-dependent methyltransferases	PrmA
Q86X55	n/a	6arj	BW4	C	502	e6arjD1	Arginine methyltransferase oligomerization subdomain	Arginine methyltransferase oligomerization subdomain	Arginine methyltransferase oligomerization subdomain	PRMT_C
Q86X55	n/a	6arj	BW4	D	502	e6arjC1	Arginine methyltransferase oligomerization subdomain	Arginine methyltransferase oligomerization subdomain	Arginine methyltransferase oligomerization subdomain	PRMT_C
Q86X55	n/a	6arj	BW4	D	502	e6arjD1	Arginine methyltransferase oligomerization subdomain	Arginine methyltransferase oligomerization subdomain	Arginine methyltransferase oligomerization subdomain	PRMT_C
Q86X55	n/a	6arj	BW4	D	502	e6arjD2	Rossmann-like	Rossmann-related	S-adenosyl-L-methionine-dependent methyltransferases	PrmA