Attributes
UniProt ID
Protein Name
Cyclic GMP-AMP synthase
Ligand Name
cGAMP
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
XRILCFTWUCUKJR-INFSMZHSSA-N
SMILES
c1nc(c2c(n1)n(cn2)C3C(C4C(O3)COP(=O)(OC5C(C(COP(=O)(O4)O)OC5n6cnc7c6NC(=NC7=O)N)O)O)O)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 4LEZ
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Color Legend
Unassigned regionsLigand / hetero atomse4lezA1e4lezA2e4lezC1e4lezC2
ECOD domains from experimental PDB structures interacting with ligand 1SY
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q8C6L5 | n/a | 1SY | 4lez | e4lezA1 | A:379-507 |
| Q8C6L5 | n/a | 1SY | 4lez | e4lezA2 | A:149-378 |
| Q8C6L5 | n/a | 1SY | 4lez | e4lezC1 | C:379-507 |
| Q8C6L5 | n/a | 1SY | 4lez | e4lezC2 | C:149-378 |
| Q8C6L5 | n/a | 1SY | 7buq | e7buqA1 | A:146-378 |
| Q8C6L5 | n/a | 1SY | 7buq | e7buqA2 | A:379-507 |
| Q8C6L5 | n/a | 1SY | 7buq | e7buqB1 | B:379-507 |
| Q8C6L5 | n/a | 1SY | 7buq | e7buqB2 | B:147-378 |