Attributes
UniProt ID
Protein Name
Cyclic GMP-AMP synthase
Ligand Name
[[(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
GILDQNNERNWCKN-MHARETSRSA-N
SMILES
c1nc2c(n1C3C(C(C(O3)COP(=O)(O)OC4C(C(OC4n5cnc6c5N=C(NC6=O)N)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)O)N=C(NC2=O)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 7UZR
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Color Legend
Unassigned regionsLigand / hetero atomse7uzrA1e7uzrA2e7uzrC1e7uzrC2
ECOD domains from experimental PDB structures interacting with ligand OKR
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q8C6L5 | n/a | OKR | 7uzr | e7uzrA1 | A:384-506 |
| Q8C6L5 | n/a | OKR | 7uzr | e7uzrA2 | A:149-383 |
| Q8C6L5 | n/a | OKR | 7uzr | e7uzrC1 | C:149-383 |
| Q8C6L5 | n/a | OKR | 7uzr | e7uzrC2 | C:384-506 |
| Q8C6L5 | n/a | OKR | 7v0c | e7v0cA1 | A:384-506 |
| Q8C6L5 | n/a | OKR | 7v0c | e7v0cA2 | A:149-383 |
| Q8C6L5 | n/a | OKR | 7v0c | e7v0cC1 | C:384-506 |
| Q8C6L5 | n/a | OKR | 7v0c | e7v0cC2 | C:149-383 |