S-Thalidomide

Q8C7D2 — Protein cereblon

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand EF2

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand EF2

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q8C7D2	n/a	4tzc	EF2	A	504	e4tzcA1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	4tzc	EF2	B	505	e4tzcB1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	4tzc	EF2	B	505	e4tzcD1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	4tzc	EF2	C	502	e4tzcC1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	4tzc	EF2	D	505	e4tzcB1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	4tzc	EF2	D	505	e4tzcD1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	A	501	e5yizA1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	D	501	e5yizD1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	G	501	e5yizG1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	G	501	e5yizY1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	J	501	e5yizJ1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	M	501	e5yizM1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	P	501	e5yizP1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	S	501	e5yizS1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	V	501	e5yizV1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	Y	501	e5yizG1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	Y	501	e5yizY1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	b	501	e5yizb1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	e	501	e5yize1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	h	501	e5yizh1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	k	501	e5yizk1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	k	501	e5yizt1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	n	501	e5yizn1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	q	501	e5yizq1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	t	501	e5yizk1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yiz	EF2	t	501	e5yizt1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	A	501	e5yj0A1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	D	501	e5yj0D1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	G	501	e5yj0G1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	G	501	e5yj0Y1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	J	501	e5yj0J1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	M	501	e5yj0M1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	P	501	e5yj0P1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	S	501	e5yj0S1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	V	501	e5yj0V1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	Y	501	e5yj0G1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	Y	501	e5yj0Y1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	b	501	e5yj0b1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	e	501	e5yj0e1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	h	501	e5yj0h1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	k	501	e5yj0k1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	k	501	e5yj0t1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	n	501	e5yj0n1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	q	501	e5yj0q1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	t	501	e5yj0k1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
Q8C7D2	n/a	5yj0	EF2	t	501	e5yj0t1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18