DrugDomain logoDrugDomain

N-(5-tert-butyl-1H-pyrazol-3-yl)-8-fluoro-2-[(2R)-2-methylpiperazin-1-yl]quinazolin-4-amine

Q8I0P1 — Spastin

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand L8M

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand L8M

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q8I0P1n/a6nywL8MB802e6nywB1Histone-likeHistone-relatedAAA+ ATPase lid domainVps4_C,AAA_lid_3
Q8I0P1n/a6nywL8MB802e6nywB2P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA