Attributes
UniProt ID
Protein Name
Proline--tRNA ligase
Ligand Name
4-[(3S)-3-cyclopropyl-3-(hydroxymethyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
SGTQLZKTLHEFII-AREMUKBSSA-N
SMILES
Cc1cc(cc(n1)C(=O)NCc2cc(cc(c2)F)c3cnn(c3)C)N4CCC(C4=O)(CO)C5CC5
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 7F97
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Color Legend
Unassigned regionsLigand / hetero atomse7f97A1e7f97A2e7f97A3e7f97B1e7f97B2e7f97B3e7f97C1e7f97C2e7f97C3e7f97D1e7f97D2e7f97D3
ECOD domains from experimental PDB structures interacting with ligand 1XK
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q8I5R7 | n/a | 1XK | 7f97 | e7f97A1 | A:640-746 |
| Q8I5R7 | n/a | 1XK | 7f97 | e7f97A3 | A:252-519 |
| Q8I5R7 | n/a | 1XK | 7f97 | e7f97B1 | B:640-746 |
| Q8I5R7 | n/a | 1XK | 7f97 | e7f97B2 | B:252-519 |
| Q8I5R7 | n/a | 1XK | 7f97 | e7f97C1 | C:640-746 |
| Q8I5R7 | n/a | 1XK | 7f97 | e7f97C3 | C:252-519 |
| Q8I5R7 | n/a | 1XK | 7f97 | e7f97D1 | D:252-519 |
| Q8I5R7 | n/a | 1XK | 7f97 | e7f97D2 | D:640-746 |