N-((2R,3S,6S,18S,21S)-2-amino-18-(4-benzoylbenzyl)-21-carbamoyl-3-hydroxy-6-(naphthalen-2-ylmethyl)-4,7,16,19-tetraoxo-1-phenyl-11,14-dioxa-5,8,17,20-tetraazapentacosan-25-yl)hex-5-ynamide

Q8IL11 — Leucine aminopeptidase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DGZ

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DGZ

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q8IL11	n/a	3t8w	DGZ	A	615	e3t8wA3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	A	615	e3t8wB3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	A	615	e3t8wF3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	B	615	e3t8wB3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	B	615	e3t8wC3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	B	615	e3t8wE3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	C	615	e3t8wA3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	C	615	e3t8wC3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	C	615	e3t8wD3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	D	615	e3t8wC3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	D	615	e3t8wD3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	D	615	e3t8wE3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	E	615	e3t8wB3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	E	615	e3t8wE3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	E	615	e3t8wF3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	F	615	e3t8wA3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	F	615	e3t8wD3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	F	615	e3t8wF3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	G	615	e3t8wG3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	G	615	e3t8wH3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	G	615	e3t8wL3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	H	615	e3t8wH3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	H	615	e3t8wK3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	I	615	e3t8wG3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	I	615	e3t8wI3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	I	615	e3t8wJ3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	J	615	e3t8wI3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	J	615	e3t8wJ3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	J	615	e3t8wK3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	K	615	e3t8wH3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	K	615	e3t8wK3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	K	615	e3t8wL3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	L	615	e3t8wG3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	L	615	e3t8wJ3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17
Q8IL11	n/a	3t8w	DGZ	L	615	e3t8wL3	Phosphorylase/hydrolase-like	Zn-dependent exopeptidases	Zn-dependent exopeptidases	Peptidase_M17