DrugDomain logoDrugDomain

[(2S,3R,4R,5R)-5-[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-2,4-bis(oxidanyl)oxolan-3-yl] tetradecanoate

Q8IXJ6 — NAD-dependent protein deacetylase sirtuin-2

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand OMR

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand OMR

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q8IXJ6n/a4y6qOMRA502e4y6qA1Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedn/a
Q8IXJ6n/a4y6qOMRA502e4y6qA2Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q8IXJ6n/a4y6qOMRA502e4y6qD1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q8IXJ6n/a4y6qOMRB502e4y6qB1Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedn/a
Q8IXJ6n/a4y6qOMRB502e4y6qB2Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q8IXJ6n/a4y6qOMRC502e4y6qC1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q8IXJ6n/a4y6qOMRC502e4y6qC2Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedn/a
Q8IXJ6n/a4y6qOMRD502e4y6qD1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q8IXJ6n/a4y6qOMRD502e4y6qD2Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedn/a
Q8IXJ6n/a6l72OMRA401e6l72A1Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedn/a
Q8IXJ6n/a6l72OMRA401e6l72A2Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2