DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
NAD-dependent protein deacylase sirtuin-6
Ligand Name
5-[[3,5-bis(chloranyl)phenyl]sulfonylamino]-2-[(5-bromanyl-4-fluoranyl-2-methyl-phenyl)sulfamoyl]benzoic acid
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
MJYYUGUIBHEWRX-UHFFFAOYSA-N
SMILES
Cc1cc(c(cc1NS(=O)(=O)c2ccc(cc2C(=O)O)NS(=O)(=O)c3cc(cc(c3)Cl)Cl)Br)F
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5Y2F
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Color Legend
Unassigned regionsLigand / hetero atomse5y2fA1e5y2fA2
ECOD domains from experimental PDB structures interacting with ligand 8L9
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q8N6T7n/a8L95y2fe5y2fA1A:133-183
Q8N6T7n/a8L95y2fe5y2fA2A:1-132,A:184-297
Q8N6T7n/a8L96xv1e6xv1A1A:135-185
Q8N6T7n/a8L96xv1e6xv1A2A:10-134,A:186-298
Q8N6T7n/a8L96xvge6xvgA1A:14-134,A:186-298
Q8N6T7n/a8L96xvge6xvgA2A:135-185
Q8N6T7n/a8L96xvge6xvgB1B:15-134,B:186-298
Q8N6T7n/a8L96xvge6xvgB2B:135-185
Q8N6T7n/a8L96xvge6xvgC1C:135-185
Q8N6T7n/a8L96xvge6xvgC2C:14-134,C:186-298
Q8N6T7n/a8L96xvge6xvgD1D:15-134,D:186-298
Q8N6T7n/a8L96xvge6xvgD2D:135-185
Q8N6T7n/a8L96xvge6xvgE1E:135-185
Q8N6T7n/a8L96xvge6xvgE2E:13-134,E:186-298
Q8N6T7n/a8L96xvge6xvgF1F:135-185
Q8N6T7n/a8L96xvge6xvgF2F:14-134,F:186-298
Q8N6T7n/a8L97cl1e7cl1A1A:133-183
Q8N6T7n/a8L97cl1e7cl1A2A:2-132,A:184-297