Attributes
UniProt ID
Protein Name
NAD-dependent protein deacylase sirtuin-6
Ligand Name
[(2R,3S,4R,5R)-4-(acetylamino)-3,5-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
YKUBGMLROVEQHG-YUGVQSHHSA-N
SMILES
CC(=O)NC1C(C(OC1O)COP(=O)(O)OP(=O)(O)OCC2C(C(C(O2)n3cnc4c3ncnc4N)O)O)O
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 3PKJ
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Color Legend
Unassigned regionsLigand / hetero atomse3pkjA1e3pkjA2e3pkjB1e3pkjB2e3pkjC1e3pkjC2e3pkjD2e3pkjD3e3pkjE1e3pkjE2e3pkjF1e3pkjF2
ECOD domains from experimental PDB structures interacting with ligand A2N
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q8N6T7 | n/a | A2N | 3pkj | e3pkjA2 | A:11-132,A:184-294 |
| Q8N6T7 | n/a | A2N | 3pkj | e3pkjB2 | B:11-132,B:184-294 |
| Q8N6T7 | n/a | A2N | 3pkj | e3pkjC1 | C:12-132,C:184-294 |
| Q8N6T7 | n/a | A2N | 3pkj | e3pkjD2 | D:14-132,D:184-295 |
| Q8N6T7 | n/a | A2N | 3pkj | e3pkjE2 | E:11-132,E:184-294 |
| Q8N6T7 | n/a | A2N | 3pkj | e3pkjF2 | F:11-132,F:184-294 |