DrugDomain logoDrugDomain

Attributes

UniProt ID
Q8N6T7
Protein Name
NAD-dependent protein deacylase sirtuin-6
Ligand Name
[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
DrugBank ID
DB02059
PDB Ligand Accession
AR6
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
SRNWOUGRCWSEMX-ZQSHOCFMSA-N
SMILES
c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)O)O)O)O)O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 3PKI
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Color Legend
Unassigned regionsLigand / hetero atomse3pkiA1e3pkiA2e3pkiB2e3pkiB3e3pkiC1e3pkiC2e3pkiD2e3pkiD3e3pkiE2e3pkiE3e3pkiF2e3pkiF3
ECOD domains from experimental PDB structures interacting with ligand DB02059
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q8N6T7DB02059AR63pkie3pkiA1A:11-132,A:184-295
Q8N6T7DB02059AR63pkie3pkiB2B:12-132,B:184-295
Q8N6T7DB02059AR63pkie3pkiC1C:12-132,C:184-294
Q8N6T7DB02059AR63pkie3pkiD2D:13-132,D:184-295
Q8N6T7DB02059AR63pkie3pkiE2E:12-132,E:184-295
Q8N6T7DB02059AR63pkie3pkiF2F:13-132,F:184-294
Q8N6T7DB02059AR65mf6e5mf6A1A:10-134,A:186-298
Q8N6T7DB02059AR65mf6e5mf6B1B:15-134,B:186-296
Q8N6T7DB02059AR65mfpe5mfpA1A:10-134,A:186-298
Q8N6T7DB02059AR65mfpe5mfpB1B:15-134,B:186-296
Q8N6T7DB02059AR65mfze5mfzA1A:10-134,A:186-298
Q8N6T7DB02059AR65mfze5mfzB1B:15-134,B:186-296
Q8N6T7DB02059AR65mgne5mgnA2A:10-134,A:186-298
Q8N6T7DB02059AR65mgne5mgnB2B:15-134,B:186-296
Q8N6T7DB02059AR65x16e5x16A1A:5-132,A:184-297
Q8N6T7DB02059AR65y2fe5y2fA2A:1-132,A:184-297
Q8N6T7DB02059AR66hoye6hoyA1A:10-134,A:186-297
Q8N6T7DB02059AR66hoye6hoyB1B:15-134,B:186-297
Q8N6T7DB02059AR66qcde6qcdA1A:10-134,A:186-298
Q8N6T7DB02059AR66qcde6qcdB1B:15-134,B:186-298
Q8N6T7DB02059AR66qcee6qceA2A:10-134,A:186-298
Q8N6T7DB02059AR66qcee6qceB2B:15-134,B:186-298
Q8N6T7DB02059AR66qche6qchA2A:10-134,A:186-297
Q8N6T7DB02059AR66qche6qchB1B:15-134,B:186-296
Q8N6T7DB02059AR66qcje6qcjA2A:10-134,A:186-298
Q8N6T7DB02059AR66qcje6qcjB1B:15-134,B:186-298
Q8N6T7DB02059AR66xuye6xuyA1A:10-134,A:186-298
Q8N6T7DB02059AR66xuye6xuyB2B:15-134,B:186-298
Q8N6T7DB02059AR66xv1e6xv1A2A:10-134,A:186-298
Q8N6T7DB02059AR66xv1e6xv1B1B:15-134,B:186-298
Q8N6T7DB02059AR66xv6e6xv6A1A:4-134,A:186-298
Q8N6T7DB02059AR66xv6e6xv6B1B:14-134,B:186-298
Q8N6T7DB02059AR66xv6e6xv6C1C:3-134,C:186-297
Q8N6T7DB02059AR66xv6e6xv6D2D:12-134,D:186-298
Q8N6T7DB02059AR66xv6e6xv6E1E:13-134,E:186-298
Q8N6T7DB02059AR66xv6e6xv6F1F:3-134,F:186-298
Q8N6T7DB02059AR66xvge6xvgA1A:14-134,A:186-298
Q8N6T7DB02059AR66xvge6xvgB1B:15-134,B:186-298
Q8N6T7DB02059AR66xvge6xvgC2C:14-134,C:186-298
Q8N6T7DB02059AR66xvge6xvgD1D:15-134,D:186-298
Q8N6T7DB02059AR66xvge6xvgE2E:13-134,E:186-298
Q8N6T7DB02059AR66xvge6xvgF2F:14-134,F:186-298
Q8N6T7DB02059AR66zu4e6zu4A1A:10-134,A:186-298
Q8N6T7DB02059AR66zu4e6zu4B2B:15-134,B:186-298
Q8N6T7DB02059AR67cl0e7cl0A1A:6-134,A:186-299
Q8N6T7DB02059AR67cl1e7cl1A2A:2-132,A:184-297
Q8N6T7DB02059AR68ak5e8ak5A2A:10-134,A:186-298
Q8N6T7DB02059AR68ak5e8ak5B2B:15-134,B:186-298
Q8N6T7DB02059AR68ak6e8ak6A1A:10-134,A:186-298
Q8N6T7DB02059AR68ak6e8ak6B1B:15-134,B:186-298
Q8N6T7DB02059AR68ak7e8ak7A2A:10-134,A:186-298
Q8N6T7DB02059AR68ak7e8ak7B1B:15-134,B:186-298
Q8N6T7DB02059AR68ak8e8ak8A2A:10-134,A:186-298
Q8N6T7DB02059AR68ak8e8ak8B1B:15-134,B:186-298
Q8N6T7DB02059AR68ak9e8ak9A1A:7-134,A:186-298
Q8N6T7DB02059AR68ak9e8ak9B1B:15-134,B:186-298
Q8N6T7DB02059AR68akae8akaA2A:10-134,A:186-298
Q8N6T7DB02059AR68akae8akaB1B:15-134,B:186-298
Q8N6T7DB02059AR68akbe8akbA1A:10-134,A:186-298
Q8N6T7DB02059AR68akbe8akbB1B:15-134,B:186-298
Q8N6T7DB02059AR68akce8akcA1A:10-134,A:186-298
Q8N6T7DB02059AR68akce8akcB1B:15-134,B:186-298
Q8N6T7DB02059AR68akde8akdA2A:10-134,A:186-298
Q8N6T7DB02059AR68akde8akdB1B:15-134,B:186-298
Q8N6T7DB02059AR68akee8akeA1A:10-134,A:186-298
Q8N6T7DB02059AR68akee8akeB2B:15-134,B:186-298
Q8N6T7DB02059AR68akfe8akfA2A:10-134,A:186-298
Q8N6T7DB02059AR68akfe8akfB2B:15-134,B:186-298
Q8N6T7DB02059AR68akge8akgA1A:10-134,A:186-298
Q8N6T7DB02059AR68akge8akgB2B:15-134,B:186-298
Q8N6T7DB02059AR68bl0e8bl0A1A:10-134,A:186-298
Q8N6T7DB02059AR68bl0e8bl0B2B:15-134,B:186-298
Q8N6T7DB02059AR68bl1e8bl1A1A:10-134,A:186-298
Q8N6T7DB02059AR68bl1e8bl1B1B:15-134,B:186-298