1,2-ETHANEDIOL

Q8N6T7 — NAD-dependent protein deacylase sirtuin-6

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand EDO

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand EDO

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q8N6T7	n/a	5mf6	EDO	A	408	e5mf6A1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	5mf6	EDO	A	408	e5mf6B1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	5mf6	EDO	B	407	e5mf6B1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	5mfp	EDO	A	409	e5mfpA1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	5mfp	EDO	A	409	e5mfpB1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	5mfp	EDO	B	409	e5mfpB1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	5mfz	EDO	B	408	e5mfzB1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	5mgn	EDO	A	408	e5mgnA2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	5mgn	EDO	B	407	e5mgnA2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	5mgn	EDO	B	407	e5mgnB2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6hoy	EDO	A	404	e6hoyA1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6hoy	EDO	B	705	e6hoyB1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6qcd	EDO	A	410	e6qcdA1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6qcd	EDO	A	410	e6qcdB1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6qce	EDO	A	412	e6qceA2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6qch	EDO	A	405	e6qchA2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6qch	EDO	A	405	e6qchB1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6qch	EDO	B	403	e6qchB1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6qcj	EDO	A	403	e6qcjA2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	7cl0	EDO	A	418	e7cl0A1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak5	EDO	A	404	e8ak5A1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	Ribosomal_L33
Q8N6T7	n/a	8ak5	EDO	A	404	e8ak5A2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak6	EDO	A	407	e8ak6A1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak6	EDO	A	407	e8ak6B1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak6	EDO	B	404	e8ak6B1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak6	EDO	B	404	e8ak6B2	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	Ribosomal_L33
Q8N6T7	n/a	8ak7	EDO	A	404	e8ak7A2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak9	EDO	A	403	e8ak9A1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8aka	EDO	B	405	e8akaB1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akb	EDO	A	405	e8akbA1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akb	EDO	A	405	e8akbB1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ake	EDO	A	404	e8akeA1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akf	EDO	B	403	e8akfB1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	Ribosomal_L33
Q8N6T7	n/a	8akf	EDO	B	403	e8akfB2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akg	EDO	A	404	e8akgA1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akg	EDO	A	404	e8akgA2	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	Ribosomal_L33
Q8N6T7	n/a	8akg	EDO	B	401	e8akgA1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akg	EDO	B	401	e8akgB2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2