DI(HYDROXYETHYL)ETHER

Q8N6T7 — NAD-dependent protein deacylase sirtuin-6

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand PEG

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand PEG

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q8N6T7	n/a	5y2f	PEG	A	415	e5y2fA2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	7cl0	PEG	D	102	e7cl0A1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	7cl1	PEG	A	409	e7cl1A2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak5	PEG	B	405	e8ak5A2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak5	PEG	B	405	e8ak5B1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	Ribosomal_L33
Q8N6T7	n/a	8ak5	PEG	B	405	e8ak5B2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak6	PEG	A	404	e8ak6A1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak6	PEG	A	404	e8ak6B1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak7	PEG	A	406	e8ak7A2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak7	PEG	A	406	e8ak7B1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak7	PEG	B	401	e8ak7A2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak7	PEG	B	401	e8ak7B1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak8	PEG	A	405	e8ak8A2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak8	PEG	A	405	e8ak8B1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak9	PEG	B	404	e8ak9A1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak9	PEG	B	404	e8ak9B1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ak9	PEG	B	404	e8ak9B2	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	Ribosomal_L33
Q8N6T7	n/a	8aka	PEG	A	404	e8akaA2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8aka	PEG	A	404	e8akaB1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8aka	PEG	B	401	e8akaA1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	Ribosomal_L33
Q8N6T7	n/a	8aka	PEG	B	401	e8akaA2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8aka	PEG	B	401	e8akaB1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akb	PEG	B	401	e8akbA1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akb	PEG	B	401	e8akbA2	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	Ribosomal_L33
Q8N6T7	n/a	8akb	PEG	B	401	e8akbB1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akc	PEG	A	404	e8akcA1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akc	PEG	A	404	e8akcB1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akc	PEG	B	404	e8akcB1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akd	PEG	A	404	e8akdA2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akd	PEG	A	404	e8akdB1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akd	PEG	B	401	e8akdA2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akd	PEG	B	401	e8akdB1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ake	PEG	A	405	e8akeA1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ake	PEG	A	405	e8akeB2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ake	PEG	B	401	e8akeA1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8ake	PEG	B	401	e8akeB2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akf	PEG	A	404	e8akfA2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akf	PEG	A	404	e8akfB2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akg	PEG	A	405	e8akgA1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8akg	PEG	A	405	e8akgB2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8bl0	PEG	B	401	e8bl0A1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8bl0	PEG	B	401	e8bl0B2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8bl1	PEG	A	404	e8bl1A1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8bl1	PEG	A	404	e8bl1A2	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	Ribosomal_L33
Q8N6T7	n/a	8bl1	PEG	A	404	e8bl1B1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8bl1	PEG	B	403	e8bl1A1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8bl1	PEG	B	403	e8bl1B1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	8bl1	PEG	B	403	e8bl1B2	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	Ribosomal_L33