DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
NAD-dependent protein deacylase sirtuin-6
Ligand Name
3-[4-[[5-(2-fluorophenyl)thiophen-2-yl]methyl]piperazin-1-yl]sulfonylbenzenesulfonamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
WDLYMEBZGQFHSM-UHFFFAOYSA-N
SMILES
c1ccc(c(c1)c2ccc(s2)CN3CCN(CC3)S(=O)(=O)c4cccc(c4)S(=O)(=O)N)F
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 8BL0
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Color Legend
Unassigned regionsLigand / hetero atomse8bl0A1e8bl0A2e8bl0B1e8bl0B2
ECOD domains from experimental PDB structures interacting with ligand QTI
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q8N6T7n/aQTI8bl0e8bl0A1A:10-134,A:186-298
Q8N6T7n/aQTI8bl0e8bl0A2A:135-185
Q8N6T7n/aQTI8bl0e8bl0B1B:135-185
Q8N6T7n/aQTI8bl0e8bl0B2B:15-134,B:186-298