Attributes
UniProt ID
Protein Name
Cyclic GMP-AMP synthase
Ligand Name
(1R,2S)-2-[(7-hydroxy-5-phenylpyrazolo[1,5-a]pyrimidine-3-carbonyl)amino]cyclohexane-1-carboxylic acid
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
PHGTYMRDHDEHLI-HIFRSBDPSA-N
SMILES
c1ccc(cc1)c2cc(n3c(n2)c(cn3)C(=O)NC4CCCCC4C(=O)O)O
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 6LRC
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Color Legend
Unassigned regionsLigand / hetero atomse6lrcA1e6lrcA2e6lrcB1e6lrcB2
ECOD domains from experimental PDB structures interacting with ligand KHM
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q8N884 | n/a | KHM | 6lrc | e6lrcA1 | A:161-395 |
| Q8N884 | n/a | KHM | 6lrc | e6lrcA2 | A:396-520 |
| Q8N884 | n/a | KHM | 6lrc | e6lrcB1 | B:396-520 |
| Q8N884 | n/a | KHM | 6lrc | e6lrcB2 | B:161-395 |
| Q8N884 | n/a | KHM | 6nao | e6naoA1 | A:396-522 |
| Q8N884 | n/a | KHM | 6nao | e6naoA2 | A:161-395 |
| Q8N884 | n/a | KHM | 6nao | e6naoB1 | B:161-395 |
| Q8N884 | n/a | KHM | 6nao | e6naoB2 | B:396-521 |