DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Mixed lineage kinase domain-like protein
Ligand Name
1-[4-[methyl-[2-[(3-sulfamoylphenyl)amino]pyrimidin-4-yl]amino]phenyl]-3-[4-(trifluoromethyloxy)phenyl]urea
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
SNRUTMWCDZHKKM-UHFFFAOYSA-N
SMILES
CN(c1ccc(cc1)NC(=O)Nc2ccc(cc2)OC(F)(F)F)c3ccnc(n3)Nc4cccc(c4)S(=O)(=O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 5KNJ
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse5knjA1e5knjB1
ECOD domains from experimental PDB structures interacting with ligand 6UX
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q8NB16n/a6UX5knje5knjA1A:193-468
Q8NB16n/a6UX5knje5knjB1B:192-349,B:369-469