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2-fluoro-4-{[(1R)-1-methyl-6-{[(2S)-oxan-2-yl]methoxy}-1-{2-oxo-2-[(1,3-thiazol-2-yl)amino]ethyl}-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}benzoic acid

Q8NBP7 — Proprotein convertase subtilisin/kexin type 9

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand PVJ

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand PVJ

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q8NBP7n/a6u38PVJB801e6u38B2Subtilisin-likeSubtilisin-likeSubtilisin-likePeptidase_S8
Q8NBP7n/a6u38PVJB801e6u38B3ResistinResistinResistinPCSK9_C1