DrugDomain logoDrugDomain

Attributes

UniProt ID
Q8PYN5
Protein Name
2,5-diamino-6--4-pyrimidinone 5'-phosphate reductase
Ligand Name
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
DrugBank ID
DB03461
PDB Ligand Accession
NAP
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
XJLXINKUBYWONI-NNYOXOHSSA-N
SMILES
c1cc(c[n+](c1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)n4cnc5c4ncnc5N)OP(=O)(O)O)O)O)O)C(=O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 5XUX
Open File
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse5xuxA1e5xuxB1e5xuxC1e5xuxD1e5xuxE1e5xuxF1
ECOD domains from experimental PDB structures interacting with ligand DB03461
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q8PYN5DB03461NAP5xuxe5xuxA1A:-9-228
Q8PYN5DB03461NAP5xuxe5xuxB1B:1-224
Q8PYN5DB03461NAP5xuxe5xuxC1C:2-225
Q8PYN5DB03461NAP5xuxe5xuxD1D:2-224
Q8PYN5DB03461NAP5xuxe5xuxE1E:2-224
Q8PYN5DB03461NAP5xuxe5xuxF1F:-9-228
Q8PYN5DB03461NAP5xv0e5xv0A1A:-9-228
Q8PYN5DB03461NAP5xv0e5xv0B1B:1-224
Q8PYN5DB03461NAP5xv0e5xv0C1C:1-224
Q8PYN5DB03461NAP5xv0e5xv0D1D:2-224
Q8PYN5DB03461NAP5xv0e5xv0E1E:2-224
Q8PYN5DB03461NAP5xv0e5xv0F1F:-10-228
Q8PYN5DB03461NAP5xv2e5xv2A1A:2-224