5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine

Q8RQE8 — DNA-directed RNA polymerase subunit beta'

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 2TM

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 2TM

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q8RQE8	n/a	4oio	2TM	D	2006	e4oioD2	cradle loop barrel	RIFT-related	double psi	RNA_pol_Rpb1_2
Q8RQE8	n/a	4oio	2TM	D	2006	e4oioD5	second helical domain in RNA-polymerase beta-prime subunit	second helical domain in RNA-polymerase beta-prime subunit	second helical domain in RNA-polymerase beta-prime subunit	RNA_pol_Rpb1_5,RNA_pol_Rpb1_4
Q8RQE8	n/a	4oio	2TM	D	2006	e4oioD7	first helical domain in RNA-polymerase beta-prime subunit	first helical domain in RNA-polymerase beta-prime subunit	first helical domain in RNA-polymerase beta-prime subunit	RNA_pol_Rpb1_3
Q8RQE8	n/a	4q4z	2TM	D	2006	e4q4zD11	cradle loop barrel	RIFT-related	double psi	RNA_pol_Rpb1_2
Q8RQE8	n/a	4q4z	2TM	D	2006	e4q4zD4	central helical domain in RNA-polymerase beta-prime subunit	central helical domain in RNA-polymerase beta-prime subunit	central helical domain in RNA-polymerase beta-prime subunit	RNA_pol_Rpb1_5
Q8RQE8	n/a	4q4z	2TM	D	2006	e4q4zD5	second helical domain in RNA-polymerase beta-prime subunit	second helical domain in RNA-polymerase beta-prime subunit	second helical domain in RNA-polymerase beta-prime subunit	RNA_pol_Rpb1_5,RNA_pol_Rpb1_4
Q8RQE8	n/a	5x22	2TM	D	2007	e5x22D11	cradle loop barrel	RIFT-related	double psi	RNA_pol_Rpb1_2
Q8RQE8	n/a	5x22	2TM	D	2007	e5x22D2	central helical domain in RNA-polymerase beta-prime subunit	central helical domain in RNA-polymerase beta-prime subunit	central helical domain in RNA-polymerase beta-prime subunit	RNA_pol_Rpb1_5
Q8RQE8	n/a	5x22	2TM	D	2007	e5x22D7	second helical domain in RNA-polymerase beta-prime subunit	second helical domain in RNA-polymerase beta-prime subunit	second helical domain in RNA-polymerase beta-prime subunit	RNA_pol_Rpb1_5,RNA_pol_Rpb1_4
Q8RQE8	n/a	5x22	2TM	N	2007	e5x22N11	central helical domain in RNA-polymerase beta-prime subunit	central helical domain in RNA-polymerase beta-prime subunit	central helical domain in RNA-polymerase beta-prime subunit	RNA_pol_Rpb1_5
Q8RQE8	n/a	5x22	2TM	N	2007	e5x22N4	second helical domain in RNA-polymerase beta-prime subunit	second helical domain in RNA-polymerase beta-prime subunit	second helical domain in RNA-polymerase beta-prime subunit	RNA_pol_Rpb1_5,RNA_pol_Rpb1_4
Q8RQE8	n/a	5x22	2TM	N	2007	e5x22N6	cradle loop barrel	RIFT-related	double psi	RNA_pol_Rpb1_2
Q8RQE8	n/a	7eh0	2TM	D	2006	e7eh0D12	second helical domain in RNA-polymerase beta-prime subunit	second helical domain in RNA-polymerase beta-prime subunit	second helical domain in RNA-polymerase beta-prime subunit	RNA_pol_Rpb1_5,RNA_pol_Rpb1_4
Q8RQE8	n/a	7eh0	2TM	D	2006	e7eh0D6	first helical domain in RNA-polymerase beta-prime subunit	first helical domain in RNA-polymerase beta-prime subunit	first helical domain in RNA-polymerase beta-prime subunit	RNA_pol_Rpb1_3
Q8RQE8	n/a	7eh0	2TM	D	2006	e7eh0D9	cradle loop barrel	RIFT-related	double psi	RNA_pol_Rpb1_2
Q8RQE8	n/a	7eh1	2TM	I	2101	e7eh1D2	second helical domain in RNA-polymerase beta-prime subunit	second helical domain in RNA-polymerase beta-prime subunit	second helical domain in RNA-polymerase beta-prime subunit	RNA_pol_Rpb1_5,RNA_pol_Rpb1_4
Q8RQE8	n/a	7eh1	2TM	I	2101	e7eh1D7	cradle loop barrel	RIFT-related	double psi	RNA_pol_Rpb1_2