5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine

Q8RQE9 — DNA-directed RNA polymerase subunit beta

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 2TM

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 2TM

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q8RQE9	n/a	4oio	2TM	D	2006	e4oioC1	barrel domain in beta subunit of DNA dependent RNA-polymerase	barrel domain in beta subunit of DNA dependent RNA-polymerase	barrel domain in beta subunit of DNA dependent RNA-polymerase	RNA_pol_Rpb2_45
Q8RQE9	n/a	4oio	2TM	D	2006	e4oioC3	N-terminal domain in beta subunit of DNA dependent RNA-polymerase	N-terminal domain in beta subunit of DNA dependent RNA-polymerase	N-terminal domain in beta subunit of DNA dependent RNA-polymerase	RNA_pol_Rpb2_1,RNA_pol_Rpb2_3
Q8RQE9	n/a	4oio	2TM	D	2006	e4oioC8	cradle loop barrel	RIFT-related	double psi	RNA_pol_Rpb2_6
Q8RQE9	n/a	4q4z	2TM	D	2006	e4q4zC1	barrel domain in beta subunit of DNA dependent RNA-polymerase	barrel domain in beta subunit of DNA dependent RNA-polymerase	barrel domain in beta subunit of DNA dependent RNA-polymerase	RNA_pol_Rpb2_45
Q8RQE9	n/a	4q4z	2TM	D	2006	e4q4zC3	N-terminal domain in beta subunit of DNA dependent RNA-polymerase	N-terminal domain in beta subunit of DNA dependent RNA-polymerase	N-terminal domain in beta subunit of DNA dependent RNA-polymerase	RNA_pol_Rpb2_1,RNA_pol_Rpb2_3
Q8RQE9	n/a	4q4z	2TM	D	2006	e4q4zC8	cradle loop barrel	RIFT-related	double psi	RNA_pol_Rpb2_6
Q8RQE9	n/a	5x22	2TM	D	2007	e5x22C1	cradle loop barrel	RIFT-related	double psi	RNA_pol_Rpb2_6
Q8RQE9	n/a	5x22	2TM	D	2007	e5x22C6	barrel domain in beta subunit of DNA dependent RNA-polymerase	barrel domain in beta subunit of DNA dependent RNA-polymerase	barrel domain in beta subunit of DNA dependent RNA-polymerase	RNA_pol_Rpb2_45
Q8RQE9	n/a	5x22	2TM	D	2007	e5x22C8	N-terminal domain in beta subunit of DNA dependent RNA-polymerase	N-terminal domain in beta subunit of DNA dependent RNA-polymerase	N-terminal domain in beta subunit of DNA dependent RNA-polymerase	RNA_pol_Rpb2_1,RNA_pol_Rpb2_3
Q8RQE9	n/a	5x22	2TM	N	2007	e5x22M1	cradle loop barrel	RIFT-related	double psi	RNA_pol_Rpb2_6
Q8RQE9	n/a	5x22	2TM	N	2007	e5x22M4	barrel domain in beta subunit of DNA dependent RNA-polymerase	barrel domain in beta subunit of DNA dependent RNA-polymerase	barrel domain in beta subunit of DNA dependent RNA-polymerase	RNA_pol_Rpb2_45
Q8RQE9	n/a	5x22	2TM	N	2007	e5x22M6	N-terminal domain in beta subunit of DNA dependent RNA-polymerase	N-terminal domain in beta subunit of DNA dependent RNA-polymerase	N-terminal domain in beta subunit of DNA dependent RNA-polymerase	RNA_pol_Rpb2_1,RNA_pol_Rpb2_3
Q8RQE9	n/a	7eh0	2TM	D	2006	e7eh0C1	cradle loop barrel	RIFT-related	double psi	RNA_pol_Rpb2_6
Q8RQE9	n/a	7eh0	2TM	D	2006	e7eh0C2	barrel domain in beta subunit of DNA dependent RNA-polymerase	barrel domain in beta subunit of DNA dependent RNA-polymerase	barrel domain in beta subunit of DNA dependent RNA-polymerase	RNA_pol_Rpb2_45
Q8RQE9	n/a	7eh0	2TM	D	2006	e7eh0C5	N-terminal domain in beta subunit of DNA dependent RNA-polymerase	N-terminal domain in beta subunit of DNA dependent RNA-polymerase	N-terminal domain in beta subunit of DNA dependent RNA-polymerase	RNA_pol_Rpb2_1,RNA_pol_Rpb2_3
Q8RQE9	n/a	7eh1	2TM	I	2101	e7eh1C2	cradle loop barrel	RIFT-related	double psi	RNA_pol_Rpb2_6
Q8RQE9	n/a	7eh1	2TM	I	2101	e7eh1C5	N-terminal domain in beta subunit of DNA dependent RNA-polymerase	N-terminal domain in beta subunit of DNA dependent RNA-polymerase	N-terminal domain in beta subunit of DNA dependent RNA-polymerase	RNA_pol_Rpb2_1,RNA_pol_Rpb2_3
Q8RQE9	n/a	7eh1	2TM	I	2101	e7eh1C6	barrel domain in beta subunit of DNA dependent RNA-polymerase	barrel domain in beta subunit of DNA dependent RNA-polymerase	barrel domain in beta subunit of DNA dependent RNA-polymerase	RNA_pol_Rpb2_45