[(1S,2S,4R)-4-{4-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl]methyl sulfamate
Q8TBC4 — NEDD8-activating enzyme E1 catalytic subunit
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand DB11759
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand DB11759
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| Q8TBC4 | DB11759 | 3gzn | B39 | I | 464 | e3gznB1 | beta-Grasp | E2-binding domain of E1 | E2-binding domain of E1 | E2_bind |
| Q8TBC4 | DB11759 | 3gzn | B39 | I | 464 | e3gznB2 | Rossmann-like | Rossmann-related | Activating enzymes of the ubiquitin-like proteins | ThiF |
| Q8TBC4 | DB11759 | 3gzn | B39 | J | 464 | e3gznD1 | beta-Grasp | E2-binding domain of E1 | E2-binding domain of E1 | E2_bind |
| Q8TBC4 | DB11759 | 3gzn | B39 | J | 464 | e3gznD2 | Rossmann-like | Rossmann-related | Activating enzymes of the ubiquitin-like proteins | ThiF |