DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Mitogen-activated protein kinase kinase kinase kinase 1
Ligand Name
N-{2-(3,3-difluoropyrrolidin-1-yl)-6-[(3R)-pyrrolidin-3-yl]pyrimidin-4-yl}-1-(propan-2-yl)-1H-pyrazolo[4,3-c]pyridin-6-amine
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
JKPAJCPZQIJPPS-CQSZACIVSA-N
SMILES
CC(C)n1c2cc(ncc2cn1)Nc3cc(nc(n3)N4CCC(C4)(F)F)C5CCNC5
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 6CQF
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse6cqfA1
ECOD domains from experimental PDB structures interacting with ligand F97
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q92918n/aF976cqfe6cqfA1A:6-293
Q92918n/aF977r9ne7r9nA1A:3-293
Q92918n/aF977r9ne7r9nB1B:4-293