DIMETHYL SULFOXIDE

Q92974 — Rho guanine nucleotide exchange factor 2

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB01093

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB01093

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q92974	DB01093	7g80	DMS	B	502	e7g80B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g81	DMS	B	503	e7g81B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g82	DMS	B	505	e7g82B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g83	DMS	B	503	e7g83B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g84	DMS	B	503	e7g84B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g85	DMS	B	505	e7g85B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g86	DMS	B	505	e7g86B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g87	DMS	B	504	e7g87B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g88	DMS	B	504	e7g88B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g89	DMS	B	504	e7g89B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8a	DMS	B	504	e7g8aB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8b	DMS	B	505	e7g8bB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8c	DMS	B	504	e7g8cB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8d	DMS	A	202	e7g8dB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8d	DMS	B	506	e7g8dB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8e	DMS	B	505	e7g8eB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8f	DMS	B	503	e7g8fB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8g	DMS	B	504	e7g8gB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8h	DMS	A	204	e7g8hB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8h	DMS	B	507	e7g8hB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8i	DMS	B	502	e7g8iB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8j	DMS	B	503	e7g8jB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8k	DMS	B	506	e7g8kB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8l	DMS	B	507	e7g8lB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8m	DMS	B	502	e7g8mB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8n	DMS	B	502	e7g8nB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8o	DMS	B	504	e7g8oB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8p	DMS	B	502	e7g8pB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8q	DMS	B	504	e7g8qB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8r	DMS	B	504	e7g8rB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8s	DMS	B	504	e7g8sB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8t	DMS	B	505	e7g8tB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8u	DMS	B	503	e7g8uB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8v	DMS	B	504	e7g8vB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8w	DMS	B	504	e7g8wB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8x	DMS	B	504	e7g8xB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8y	DMS	B	504	e7g8yB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8z	DMS	A	202	e7g8zB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g8z	DMS	B	506	e7g8zB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g90	DMS	B	504	e7g90B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g91	DMS	B	502	e7g91B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g92	DMS	B	504	e7g92B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g93	DMS	B	504	e7g93B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g94	DMS	B	505	e7g94B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g95	DMS	B	505	e7g95B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g96	DMS	B	502	e7g96B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g97	DMS	A	203	e7g97B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g97	DMS	B	501	e7g97B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g98	DMS	B	502	e7g98B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g99	DMS	A	204	e7g99B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g99	DMS	B	504	e7g99B1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g9a	DMS	B	502	e7g9aB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g9b	DMS	B	502	e7g9bB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g9c	DMS	B	505	e7g9cB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g9d	DMS	B	502	e7g9dB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g9e	DMS	B	505	e7g9eB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g9f	DMS	A	202	e7g9fB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g9f	DMS	B	503	e7g9fB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g9g	DMS	B	503	e7g9gB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g9h	DMS	B	502	e7g9hB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g9i	DMS	B	503	e7g9iB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g9j	DMS	A	503	e7g9jB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	7g9j	DMS	B	503	e7g9jB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF
Q92974	DB01093	8bnt	DMS	B	504	e8bntB1	DH domain-like	DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	RhoGEF