Attributes
UniProt ID
Protein Name
Serine hydroxymethyltransferase 2, mitochondrial
Ligand Name
[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
ODVKKQWXKRZJLG-VIFPVBQESA-N
SMILES
Cc1c(c(c(cn1)COP(=O)(O)O)CNC(CO)C(=O)O)O
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 6SMN
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Color Legend
Unassigned regionsLigand / hetero atomse6smnA1e6smnA2e6smnB1e6smnB2e6smnC1e6smnC2e6smnD1e6smnD2
ECOD domains from experimental PDB structures interacting with ligand PLS
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q94C74 | n/a | PLS | 6smn | e6smnA1 | A:350-517 |
| Q94C74 | n/a | PLS | 6smn | e6smnA2 | A:43-349 |
| Q94C74 | n/a | PLS | 6smn | e6smnB1 | B:350-517 |
| Q94C74 | n/a | PLS | 6smn | e6smnB2 | B:43-349 |
| Q94C74 | n/a | PLS | 6smn | e6smnC1 | C:350-517 |
| Q94C74 | n/a | PLS | 6smn | e6smnC2 | C:43-349 |
| Q94C74 | n/a | PLS | 6smn | e6smnD1 | D:38-349 |
| Q94C74 | n/a | PLS | 6smw | e6smwA1 | A:43-349 |
| Q94C74 | n/a | PLS | 6smw | e6smwA2 | A:350-517 |
| Q94C74 | n/a | PLS | 6smw | e6smwB1 | B:43-349 |
| Q94C74 | n/a | PLS | 6smw | e6smwB2 | B:350-517 |
| Q94C74 | n/a | PLS | 6smw | e6smwC1 | C:350-517 |
| Q94C74 | n/a | PLS | 6smw | e6smwC2 | C:43-349 |
| Q94C74 | n/a | PLS | 6smw | e6smwD2 | D:38-349 |