2-[3-[2,6-bis(fluoranyl)-4-(1~{H}-pyrazol-4-yl)phenyl]-3-oxidanylidene-propyl]-4-(1-methylpyrazol-4-yl)benzoic acid

Q96EP0 — E3 ubiquitin-protein ligase RNF31

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand D60

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand D60

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q96EP0	n/a	6kc6	D60	A	1105	e6kc6A1	E3 ligase HOIP C-terminal domain	E3 ligase HOIP C-terminal domain	E3 ligase HOIP C-terminal domain	E3_UbLigase_RBR
Q96EP0	n/a	6kc6	D60	A	1105	e6kc6A2	RING/U-box-like	RING/U-box-like	IBR domain	IBR_1
Q96EP0	n/a	6kc6	D60	A	1105	e6kc6I2	RING/U-box-like	RING/U-box-like	IBR domain	IBR_1
Q96EP0	n/a	6kc6	D60	C	1105	e6kc6C1	RING/U-box-like	RING/U-box-like	IBR domain	IBR_1
Q96EP0	n/a	6kc6	D60	C	1105	e6kc6C2	E3 ligase HOIP C-terminal domain	E3 ligase HOIP C-terminal domain	E3 ligase HOIP C-terminal domain	E3_UbLigase_RBR
Q96EP0	n/a	6kc6	D60	C	1105	e6kc6K2	RING/U-box-like	RING/U-box-like	IBR domain	IBR_1
Q96EP0	n/a	6kc6	D60	E	1105	e6kc6E1	RING/U-box-like	RING/U-box-like	IBR domain	IBR_1
Q96EP0	n/a	6kc6	D60	E	1105	e6kc6E2	E3 ligase HOIP C-terminal domain	E3 ligase HOIP C-terminal domain	E3 ligase HOIP C-terminal domain	E3_UbLigase_RBR
Q96EP0	n/a	6kc6	D60	G	1105	e6kc6G1	RING/U-box-like	RING/U-box-like	IBR domain	IBR_1
Q96EP0	n/a	6kc6	D60	G	1105	e6kc6G2	E3 ligase HOIP C-terminal domain	E3 ligase HOIP C-terminal domain	E3 ligase HOIP C-terminal domain	E3_UbLigase_RBR
Q96EP0	n/a	6kc6	D60	I	1105	e6kc6A2	RING/U-box-like	RING/U-box-like	IBR domain	IBR_1
Q96EP0	n/a	6kc6	D60	I	1105	e6kc6I1	E3 ligase HOIP C-terminal domain	E3 ligase HOIP C-terminal domain	E3 ligase HOIP C-terminal domain	E3_UbLigase_RBR
Q96EP0	n/a	6kc6	D60	I	1105	e6kc6I2	RING/U-box-like	RING/U-box-like	IBR domain	IBR_1
Q96EP0	n/a	6kc6	D60	K	1105	e6kc6C1	RING/U-box-like	RING/U-box-like	IBR domain	IBR_1
Q96EP0	n/a	6kc6	D60	K	1105	e6kc6K1	E3 ligase HOIP C-terminal domain	E3 ligase HOIP C-terminal domain	E3 ligase HOIP C-terminal domain	E3_UbLigase_RBR
Q96EP0	n/a	6kc6	D60	K	1105	e6kc6K2	RING/U-box-like	RING/U-box-like	IBR domain	IBR_1