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3-methoxy-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}-1-(pyrazin-2-yl)-1H-pyrazole-4-carboxamide

Q99683 — Mitogen-activated protein kinase kinase kinase 5

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand RFG

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand RFG

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q99683n/a6vreRFGA1002e6vreA1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
Q99683n/a6vreRFGB1001e6vreB1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
Q99683n/a7mu7RFGA1003e7mu7A1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
Q99683n/a7mu7RFGB1003e7mu7B1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase