Attributes
UniProt ID
Protein Name
Alpha-ketoglutarate-dependent dioxygenase FTO -)-demethylase FTO) -methyladenosine-demethylase FTO) -)-demethylase FTO) -demethylase FTO) -methyladenosine demethylase FTO
Ligand Name
2-OXOGLUTARIC ACID
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
KPGXRSRHYNQIFN-UHFFFAOYSA-N
SMILES
C(CC(=O)O)C(=O)C(=O)O
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 4ZS2
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Color Legend
Unassigned regionsLigand / hetero atomse4zs2A1e4zs2A2
ECOD domains from experimental PDB structures interacting with ligand DB08845
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q9C0B1 | DB08845 | AKG | 4zs2 | e4zs2A1 | A:28-162,A:189-316 |
| Q9C0B1 | DB08845 | AKG | 4zs2 | e4zs2A2 | A:317-503 |
| Q9C0B1 | DB08845 | AKG | 4zs3 | e4zs3A1 | A:317-503 |
| Q9C0B1 | DB08845 | AKG | 4zs3 | e4zs3A2 | A:28-162,A:189-316 |
| Q9C0B1 | DB08845 | AKG | 5dab | e5dabA2 | A:27-161,A:188-316 |
| Q9C0B1 | DB08845 | AKG | 5dab | e5dabA3 | A:316-500 |
| Q9C0B1 | DB08845 | AKG | 5f8p | e5f8pA1 | A:27-161,A:189-316 |
| Q9C0B1 | DB08845 | AKG | 5f8p | e5f8pA2 | A:317-502 |
| Q9C0B1 | DB08845 | AKG | 6akw | e6akwA1 | A:28-163,A:188-327 |
| Q9C0B1 | DB08845 | AKG | 6akw | e6akwA2 | A:316-502 |
| Q9C0B1 | DB08845 | AKG | 7wcv | e7wcvA1 | A:316-502 |
| Q9C0B1 | DB08845 | AKG | 7wcv | e7wcvA2 | A:28-163,A:188-327 |