DrugDomain logoDrugDomain

(2S,4aR,6R,7R,7aR)-6-{6-amino-8-[(4-chlorophenyl)sulfanyl]-9H-purin-9-yl}-7-methoxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-ol 2-oxide

Q9EQZ6 — Rap guanine nucleotide exchange factor 4

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand H07

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand H07

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q9EQZ6n/a4mgyH07E1001e4mgyE1Repetitive alpha hairpinsRas GEFRas GEFRasGEF_N
Q9EQZ6n/a4mgyH07E1001e4mgyE2jelly-rollDouble-stranded beta-helixDouble-stranded beta-helixcNMP_binding