DrugDomain logoDrugDomain

(2S,4aR,6R,7R,7aS)-6-{6-amino-8-[(4-fluorobenzyl)sulfanyl]-9H-purin-9-yl}-2-sulfanyltetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol 2-oxide

Q9EQZ6 — Rap guanine nucleotide exchange factor 4

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand HR4

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand HR4

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q9EQZ6n/a4mh0HR4E1002e4mh0E1Repetitive alpha hairpinsRas GEFRas GEFRasGEF_N
Q9EQZ6n/a4mh0HR4E1002e4mh0E2jelly-rollDouble-stranded beta-helixDouble-stranded beta-helixcNMP_binding