3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Q9H3S4 — Thiamine pyrophosphokinase 1
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand DB00152
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| Q9H3S4 | DB00152 | VIB | nD1 | 7562.1.1 | Thiamin pyrophosphokinase, catalytic domain | Thiamin pyrophosphokinase, catalytic domain | Thiamin pyrophosphokinase, catalytic domain | TPK_catalytic |
| Q9H3S4 | DB00152 | VIB | nD2 | 10.11.1 | jelly-roll | Thiamin pyrophosphokinase, substrate-binding domain | Thiamin pyrophosphokinase, substrate-binding domain | TPK_B1_binding |
Show other predicted domains (4)
| PDB ID | Domain Name | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|
| 3S4Y | e3s4yA1 | 10.11.1 | jelly-roll | Thiamin pyrophosphokinase, substrate-binding domain | Thiamin pyrophosphokinase, substrate-binding domain | TPK_B1_binding |
| e3s4yB1 | 10.11.1 | jelly-roll | Thiamin pyrophosphokinase, substrate-binding domain | Thiamin pyrophosphokinase, substrate-binding domain | TPK_B1_binding | |
| e3s4yA2 | 7562.1.1 | Thiamin pyrophosphokinase, catalytic domain | Thiamin pyrophosphokinase, catalytic domain | Thiamin pyrophosphokinase, catalytic domain | TPK_catalytic | |
| e3s4yB2 | 7562.1.1 | Thiamin pyrophosphokinase, catalytic domain | Thiamin pyrophosphokinase, catalytic domain | Thiamin pyrophosphokinase, catalytic domain | TPK_catalytic |
ECOD domains from experimental PDB structures interacting with ligand DB00152
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| No experimental ECOD data found | ||||||||||