5-cyclopropyl-6-(2,6-dimethylpyridin-4-yl)-~{N}-[(3~{R},4~{R})-3-fluoranylpiperidin-4-yl]-1~{H}-indazol-3-amine
Q9NR97 — Toll-like receptor 8
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand I5N
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand I5N
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| Q9NR97 | n/a | 7r53 | I5N | A | 908 | e7r53A1 | Single-stranded right-handed beta-helix | Leucine-rich repeats | Leucine-rich repeats | LRR_8 |
| Q9NR97 | n/a | 7r53 | I5N | A | 908 | e7r53A2 | Single-stranded right-handed beta-helix | Leucine-rich repeats | Leucine-rich repeats | LRR_8 |
| Q9NR97 | n/a | 7r53 | I5N | A | 908 | e7r53B1 | Single-stranded right-handed beta-helix | Leucine-rich repeats | Leucine-rich repeats | LRR_8 |