5-[(3~{R},5~{S})-3-azanyl-5-(trifluoromethyl)piperidin-1-yl]quinoline-8-carbonitrile
Q9NR97 — Toll-like receptor 8
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand DB16501
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand DB16501
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| Q9NR97 | DB16501 | 6zjz | QLH | A | 921 | e6zjzA1 | Single-stranded right-handed beta-helix | Leucine-rich repeats | Leucine-rich repeats | LRR_8 |
| Q9NR97 | DB16501 | 6zjz | QLH | A | 921 | e6zjzA2 | Single-stranded right-handed beta-helix | Leucine-rich repeats | Leucine-rich repeats | LRR_8 |
| Q9NR97 | DB16501 | 6zjz | QLH | A | 921 | e6zjzB2 | Single-stranded right-handed beta-helix | Leucine-rich repeats | Leucine-rich repeats | LRR_8 |
| Q9NR97 | DB16501 | 6zjz | QLH | B | 918 | e6zjzA1 | Single-stranded right-handed beta-helix | Leucine-rich repeats | Leucine-rich repeats | LRR_8 |
| Q9NR97 | DB16501 | 6zjz | QLH | B | 918 | e6zjzB1 | Single-stranded right-handed beta-helix | Leucine-rich repeats | Leucine-rich repeats | LRR_8 |