Attributes
UniProt ID
Protein Name
Toll-like receptor 8
Ligand Name
(2R)-2-[(2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-yl)amino]-2-methylhexan-1-ol
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
HTCJUBZBSJQWBW-CQSZACIVSA-N
SMILES
CCCCC(C)(CO)Nc1c2c(cc(cn2)F)nc(n1)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 6WML
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Color Legend
Unassigned regionsLigand / hetero atomse6wmlA1e6wmlA2e6wmlB1e6wmlB2e6wmlC1e6wmlC2e6wmlD1e6wmlD2
ECOD domains from experimental PDB structures interacting with ligand U57
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q9NR97 | n/a | U57 | 6wml | e6wmlA1 | A:459-818 |
| Q9NR97 | n/a | U57 | 6wml | e6wmlA2 | A:31-433 |
| Q9NR97 | n/a | U57 | 6wml | e6wmlB1 | B:31-433 |
| Q9NR97 | n/a | U57 | 6wml | e6wmlB2 | B:459-818 |
| Q9NR97 | n/a | U57 | 6wml | e6wmlC1 | C:459-772,C:793-802 |
| Q9NR97 | n/a | U57 | 6wml | e6wmlC2 | C:31-433 |
| Q9NR97 | n/a | U57 | 6wml | e6wmlD1 | D:459-815 |
| Q9NR97 | n/a | U57 | 6wml | e6wmlD2 | D:33-433 |