DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Toll-like receptor 8
Ligand Name
(3~{S})-~{N}-[4-[[5-(1,6-dimethylpyrazolo[3,4-b]pyridin-4-yl)-3-methyl-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridin-1-yl]methyl]-1-bicyclo[2.2.2]octanyl]morpholine-3-carboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
OXDQXRVWDYGAHX-WTWMYVDVSA-N
SMILES
Cc1cc(c2cnn(c2n1)C)N3CCc4c(c(nn4CC56CCC(CC5)(CC6)NC(=O)C7COCCN7)C)C3
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 8PFI
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Color Legend
Unassigned regionsLigand / hetero atomse8pfiA1e8pfiA2e8pfiB1e8pfiB2
ECOD domains from experimental PDB structures interacting with ligand YHG
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q9NR97n/aYHG8pfie8pfiA1A:462-818
Q9NR97n/aYHG8pfie8pfiA2A:31-432
Q9NR97n/aYHG8pfie8pfiB1B:462-818
Q9NR97n/aYHG8pfie8pfiB2B:31-433