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N-{2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl}quinoxaline-2-carboxamide

Q9NTG7 — NAD-dependent protein deacetylase sirtuin-3, mitochondrial

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB17057

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB17057

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q9NTG7DB170574bn5SR7A1396e4bn5A1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q9NTG7DB170574bn5SR7A1396e4bn5A2Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedSIR2
Q9NTG7DB170574bn5SR7A1396e4bn5B1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q9NTG7DB170574bn5SR7B1396e4bn5A1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q9NTG7DB170574bn5SR7B1396e4bn5B1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q9NTG7DB170574bn5SR7B1396e4bn5B2Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedSIR2
Q9NTG7DB170574bn5SR7C1397e4bn5C1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q9NTG7DB170574bn5SR7C1397e4bn5C2Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedSIR2
Q9NTG7DB170574bn5SR7C1397e4bn5D1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q9NTG7DB170574bn5SR7D1396e4bn5D1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q9NTG7DB170574bn5SR7D1396e4bn5D2Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedSIR2
Q9NTG7DB170574bn5SR7E1396e4bn5E1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q9NTG7DB170574bn5SR7E1396e4bn5E2Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedSIR2
Q9NTG7DB170574bn5SR7F1396e4bn5F1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q9NTG7DB170574bn5SR7F1396e4bn5F2Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedSIR2
Q9NTG7DB170574bn5SR7G1396e4bn5G1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q9NTG7DB170574bn5SR7G1396e4bn5G2Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedSIR2
Q9NTG7DB170574bn5SR7H1396e4bn5H1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q9NTG7DB170574bn5SR7H1396e4bn5H2Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedSIR2
Q9NTG7DB170574bn5SR7I1396e4bn5I1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q9NTG7DB170574bn5SR7I1396e4bn5I2Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedSIR2
Q9NTG7DB170574bn5SR7J1396e4bn5J1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q9NTG7DB170574bn5SR7J1396e4bn5J2Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedSIR2
Q9NTG7DB170574bn5SR7K1397e4bn5K1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q9NTG7DB170574bn5SR7K1397e4bn5K2Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedSIR2
Q9NTG7DB170574bn5SR7K1397e4bn5L1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q9NTG7DB170574bn5SR7L1397e4bn5L1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q9NTG7DB170574bn5SR7L1397e4bn5L2Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedSIR2