[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE

Q9NXA8 — NAD-dependent protein deacylase sirtuin-5, mitochondrial

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB02059

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
Q9NXA8	DB02059	AR6	nD1	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2

Show other predicted domains (56)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
2B4Y	e2b4yA2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e2b4yB2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e2b4yC2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e2b4yD2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e2b4yA1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
	e2b4yB1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
	e2b4yC1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
	e2b4yD1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
2NYR	e2nyrA2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e2nyrB2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e2nyrA1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
	e2nyrB1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
3RIG	e3rigA2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e3rigB2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e3rigA1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
	e3rigB1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
3RIY	e3riyA2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e3riyB2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e3riyA1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
	e3riyB1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
4F4U	e4f4uA2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e4f4uB4	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e4f4uA1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
	e4f4uB3	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
4F56	e4f56B2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e4f56A2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e4f56B1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
	e4f56A1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
4G1C	e4g1cA2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e4g1cB2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e4g1cA1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
	e4g1cB1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
4HDA	e4hdaB2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e4hdaA4	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e4hdaB1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
	e4hdaA3	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
5BWL	e5bwlA2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
5BWL	e5bwlA1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
5XHS	e5xhsA1	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
5XHS	e5xhsA2	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
6ACE	e6aceA1	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
6ACE	e6aceA2	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
6ACL	e6aclA2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
6ACL	e6aclA1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
6ACO	e6acoA1	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
6ACO	e6acoA2	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
6ACP	e6acpA1	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
6ACP	e6acpA2	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
6EQS	e6eqsA2	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e6eqsB1	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e6eqsC1	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e6eqsD1	2003.1.4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
	e6eqsA1	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
	e6eqsB2	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
	e6eqsC2	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1
	e6eqsD2	375.1.1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	tRNA-synt_1

ECOD domains from experimental PDB structures interacting with ligand DB02059

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
No experimental ECOD data found