DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Leucine--tRNA ligase, cytoplasmic
Ligand Name
5'-O-(L-leucylsulfamoyl)adenosine
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
XFEDFDTWJLGMBO-LEJQEAHTSA-N
SMILES
CC(C)CC(C(=O)NS(=O)(=O)OCC1C(C(C(O1)n2cnc3c2ncnc3N)O)O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 6KIE
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse6kieA1e6kieA2e6kieA3e6kieA4e6kieA5e6kieA6
ECOD domains from experimental PDB structures interacting with ligand LSS
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q9P2J5n/aLSS6kiee6kieA2A:7-118,A:154-230,A:576-709
Q9P2J5n/aLSS6kiee6kieA3A:710-893
Q9P2J5n/aLSS6kr7e6kr7A2A:7-118,A:156-230,A:576-709
Q9P2J5n/aLSS6kr7e6kr7A3A:710-893
Q9P2J5n/aLSS6lpfe6lpfA2A:7-118,A:156-230,A:576-709
Q9P2J5n/aLSS6lpfe6lpfA3A:710-893
Q9P2J5n/aLSS6lpfe6lpfB2B:7-118,B:155-230,B:576-709
Q9P2J5n/aLSS6lpfe6lpfB3B:710-893
Q9P2J5n/aLSS6lr6e6lr6A2A:7-118,A:156-230,A:576-709
Q9P2J5n/aLSS6lr6e6lr6A3A:710-893
Q9P2J5n/aLSS6lr6e6lr6B2B:7-118,B:155-230,B:576-709
Q9P2J5n/aLSS6lr6e6lr6B3B:710-893