Attributes
UniProt ID
Protein Name
eIF-2-alpha kinase GCN2
Ligand Name
(2~{S})-~{N}-[(1~{S})-1-[4-[(6-pyridin-4-ylquinazolin-2-yl)amino]phenyl]ethyl]piperidine-2-carboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
OQQHJQAFUOXHSI-BVZFJXPGSA-N
SMILES
CC(c1ccc(cc1)Nc2ncc3cc(ccc3n2)c4ccncc4)NC(=O)C5CCCCN5
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 7QWK
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Color Legend
Unassigned regionsLigand / hetero atomse7qwkA1e7qwkB1e7qwkC1e7qwkD1e7qwkE1e7qwkF1e7qwkG1e7qwkH1
ECOD domains from experimental PDB structures interacting with ligand G41
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q9P2K8 | n/a | G41 | 7qwk | e7qwkA1 | A:583-659,A:795-869,A:903-998 |
| Q9P2K8 | n/a | G41 | 7qwk | e7qwkB1 | B:583-659,B:795-876,B:903-998 |
| Q9P2K8 | n/a | G41 | 7qwk | e7qwkC1 | C:583-659,C:795-873,C:904-1004 |
| Q9P2K8 | n/a | G41 | 7qwk | e7qwkD1 | D:583-659,D:795-874,D:903-1003 |
| Q9P2K8 | n/a | G41 | 7qwk | e7qwkE1 | E:584-659,E:795-869,E:913-1004 |
| Q9P2K8 | n/a | G41 | 7qwk | e7qwkF1 | F:584-659,F:795-872,F:898-1005 |
| Q9P2K8 | n/a | G41 | 7qwk | e7qwkG1 | G:584-659,G:795-878,G:904-1007 |
| Q9P2K8 | n/a | G41 | 7qwk | e7qwkH1 | H:584-659,H:795-872,H:898-1006 |