~{tert}-butyl 3-[(2~{S},5~{S},8~{S})-14-cyclopentyloxy-2-(2-methylpropyl)-4,7-bis(oxidanylidene)-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11,13,15-tetraen-5-yl]propanoate

Q9UNQ0 — Broad substrate specificity ATP-binding cassette transporter ABCG2

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand BWQ

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand BWQ

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q9UNQ0	n/a	6eti	BWQ	A	1101	e6etiA1	Type II ABC exporter transmembrane domain fold	Type II ABC exporter transmembrane domain-related	ABCG5/ABCG8 transmembrane domain	ABC2_membrane
Q9UNQ0	n/a	6eti	BWQ	A	1101	e6etiB2	Type II ABC exporter transmembrane domain fold	Type II ABC exporter transmembrane domain-related	ABCG5/ABCG8 transmembrane domain	ABC2_membrane
Q9UNQ0	n/a	6eti	BWQ	B	1101	e6etiA1	Type II ABC exporter transmembrane domain fold	Type II ABC exporter transmembrane domain-related	ABCG5/ABCG8 transmembrane domain	ABC2_membrane
Q9UNQ0	n/a	6eti	BWQ	B	1101	e6etiB2	Type II ABC exporter transmembrane domain fold	Type II ABC exporter transmembrane domain-related	ABCG5/ABCG8 transmembrane domain	ABC2_membrane
Q9UNQ0	n/a	6ffc	BWQ	A	701	e6ffcA1	Type II ABC exporter transmembrane domain fold	Type II ABC exporter transmembrane domain-related	ABCG5/ABCG8 transmembrane domain	ABC2_membrane
Q9UNQ0	n/a	6ffc	BWQ	A	701	e6ffcB1	Type II ABC exporter transmembrane domain fold	Type II ABC exporter transmembrane domain-related	ABCG5/ABCG8 transmembrane domain	ABC2_membrane
Q9UNQ0	n/a	6ffc	BWQ	B	701	e6ffcA1	Type II ABC exporter transmembrane domain fold	Type II ABC exporter transmembrane domain-related	ABCG5/ABCG8 transmembrane domain	ABC2_membrane
Q9UNQ0	n/a	6ffc	BWQ	B	701	e6ffcB1	Type II ABC exporter transmembrane domain fold	Type II ABC exporter transmembrane domain-related	ABCG5/ABCG8 transmembrane domain	ABC2_membrane
Q9UNQ0	n/a	6hij	BWQ	A	710	e6hijA1	Type II ABC exporter transmembrane domain fold	Type II ABC exporter transmembrane domain-related	ABCG5/ABCG8 transmembrane domain	ABC2_membrane
Q9UNQ0	n/a	6hij	BWQ	A	710	e6hijB2	Type II ABC exporter transmembrane domain fold	Type II ABC exporter transmembrane domain-related	ABCG5/ABCG8 transmembrane domain	ABC2_membrane
Q9UNQ0	n/a	6hij	BWQ	B	710	e6hijA1	Type II ABC exporter transmembrane domain fold	Type II ABC exporter transmembrane domain-related	ABCG5/ABCG8 transmembrane domain	ABC2_membrane
Q9UNQ0	n/a	6hij	BWQ	B	710	e6hijB2	Type II ABC exporter transmembrane domain fold	Type II ABC exporter transmembrane domain-related	ABCG5/ABCG8 transmembrane domain	ABC2_membrane