4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE
Q9UNQ0 — Broad substrate specificity ATP-binding cassette transporter ABCG2
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand DB00619
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand DB00619
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| Q9UNQ0 | DB00619 | 6vxh | STI | B | 701 | e6vxhA1 | Type II ABC exporter transmembrane domain fold | Type II ABC exporter transmembrane domain-related | ABCG5/ABCG8 transmembrane domain | ABC2_membrane |
| Q9UNQ0 | DB00619 | 6vxh | STI | B | 701 | e6vxhB2 | Type II ABC exporter transmembrane domain fold | Type II ABC exporter transmembrane domain-related | ABCG5/ABCG8 transmembrane domain | ABC2_membrane |