Attributes
UniProt ID
Protein Name
Flavin-dependent thymidylate synthase
Ligand Name
DIHYDROFLAVINE-ADENINE DINUCLEOTIDE
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
YPZRHBJKEMOYQH-UYBVJOGSSA-N
SMILES
Cc1cc2c(cc1C)N(C3=C(N2)C(=O)NC(=O)N3)CC(C(C(COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)n5cnc6c5ncnc6N)O)O)O)O)O
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 4KAT
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Color Legend
Unassigned regionsLigand / hetero atomse4katA1e4katB1e4katC1e4katD1
ECOD domains from experimental PDB structures interacting with ligand FDA
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q9WYT0 | n/a | FDA | 4kat | e4katA1 | A:-1-216 |
| Q9WYT0 | n/a | FDA | 4kat | e4katB1 | B:0-219 |
| Q9WYT0 | n/a | FDA | 4kat | e4katC1 | C:1-218 |
| Q9WYT0 | n/a | FDA | 4kat | e4katD1 | D:0-218 |
| Q9WYT0 | n/a | FDA | 7ndw | e7ndwA1 | A:1-218 |
| Q9WYT0 | n/a | FDA | 7ndw | e7ndwB1 | B:0-218 |
| Q9WYT0 | n/a | FDA | 7ndw | e7ndwC1 | C:1-219 |
| Q9WYT0 | n/a | FDA | 7ndw | e7ndwD1 | D:-1-216 |
| Q9WYT0 | n/a | FDA | 7ndz | e7ndzB1 | B:0-219 |
| Q9WYT0 | n/a | FDA | 7ndz | e7ndzC1 | C:0-219 |
| Q9WYT0 | n/a | FDA | 7ndz | e7ndzD1 | D:1-216 |