Attributes
UniProt ID
Protein Name
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Ligand Name
{(4S)-2-cyclopropyl-6-[(1-methyl-4-phenyl-1H-imidazol-2-yl)ethynyl]imidazo[1,2-b]pyridazin-3-yl}methanol
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
NRZGQNLAJIVVOU-UHFFFAOYSA-N
SMILES
Cn1cc(nc1C#Cc2ccc3nc(c(n3n2)CO)C4CC4)c5ccccc5
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 5SEY
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Color Legend
Unassigned regionsLigand / hetero atomse5seyA1e5seyB1e5seyC1e5seyD1
ECOD domains from experimental PDB structures interacting with ligand IIR
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q9Y233 | n/a | IIR | 5sey | e5seyA1 | A:458-770 |
| Q9Y233 | n/a | IIR | 5sey | e5seyB1 | B:457-771 |
| Q9Y233 | n/a | IIR | 5sey | e5seyC1 | C:458-770 |
| Q9Y233 | n/a | IIR | 5sey | e5seyD1 | D:459-768 |
| Q9Y233 | n/a | IIR | 5sk3 | e5sk3A1 | A:458-770 |
| Q9Y233 | n/a | IIR | 5sk3 | e5sk3B1 | B:457-771 |
| Q9Y233 | n/a | IIR | 5sk3 | e5sk3C1 | C:458-770 |
| Q9Y233 | n/a | IIR | 5sk3 | e5sk3D1 | D:459-768 |