DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Ligand Name
(8S)-6,7-dimethyl-2-{2-[1-methyl-3-(pyrrolidin-1-yl)-1H-1,2,4-triazol-5-yl]ethyl}-N-(propan-2-yl)imidazo[2,1-f][1,2,4]triazin-4-amine
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
QSNCXYJSYCNVBS-UHFFFAOYSA-N
SMILES
Cc1c(n2c(n1)c(nc(n2)CCc3nc(nn3C)N4CCCC4)NC(C)C)C
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5SF6
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Color Legend
Unassigned regionsLigand / hetero atomse5sf6A1e5sf6B1e5sf6C1e5sf6D1
ECOD domains from experimental PDB structures interacting with ligand IJK
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q9Y233n/aIJK5sf6e5sf6A1A:458-770
Q9Y233n/aIJK5sf6e5sf6B1B:457-771
Q9Y233n/aIJK5sf6e5sf6C1C:458-770
Q9Y233n/aIJK5sf6e5sf6D1D:458-768