DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Ligand Name
N-[(3R)-1-(5-chloropyridin-2-yl)pyrrolidin-3-yl]-6-cyclopropyl-3-[(pyrimidin-5-yl)amino]pyridine-2-carboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
XJCFZMWDELWZKB-MRXNPFEDSA-N
SMILES
c1cc(ncc1Cl)N2CCC(C2)NC(=O)c3c(ccc(n3)C4CC4)Nc5cncnc5
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5SFG
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Color Legend
Unassigned regionsLigand / hetero atomse5sfgA1e5sfgB1e5sfgC1e5sfgD1
ECOD domains from experimental PDB structures interacting with ligand IKK
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q9Y233n/aIKK5sfge5sfgA1A:458-770
Q9Y233n/aIKK5sfge5sfgB1B:457-771
Q9Y233n/aIKK5sfge5sfgC1C:458-770
Q9Y233n/aIKK5sfge5sfgD1D:459-768