DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Ligand Name
1-methyl-N~5~-[(4R)-2-phenylimidazo[1,2-a]pyrimidin-7-yl]-N~4~-[(pyridin-2-yl)methyl]-1H-pyrazole-4,5-dicarboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
RWQPESJHMNDXMR-UHFFFAOYSA-N
SMILES
Cn1c(c(cn1)C(=O)NCc2ccccn2)C(=O)Nc3ccn4cc(nc4n3)c5ccccc5
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5SFJ
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Color Legend
Unassigned regionsLigand / hetero atomse5sfjA1e5sfjB1e5sfjC1e5sfjD1
ECOD domains from experimental PDB structures interacting with ligand IKZ
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q9Y233n/aIKZ5sfje5sfjA1A:458-770
Q9Y233n/aIKZ5sfje5sfjB1B:457-771
Q9Y233n/aIKZ5sfje5sfjC1C:458-770
Q9Y233n/aIKZ5sfje5sfjD1D:459-768