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Attributes

UniProt ID
Protein Name
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Ligand Name
N~4~-ethyl-N~5~-{(4S)-2-[3-(2-fluoroethoxy)phenyl]imidazo[1,2-a]pyrimidin-7-yl}-N~4~,1-dimethyl-1H-pyrazole-4,5-dicarboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
JLXJSPCIVMCQRR-UHFFFAOYSA-N
SMILES
CCN(C)C(=O)c1cnn(c1C(=O)Nc2ccn3cc(nc3n2)c4cccc(c4)OCCF)C
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5SFR
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Color Legend
Unassigned regionsLigand / hetero atomse5sfrA1e5sfrB1e5sfrC1e5sfrD1
ECOD domains from experimental PDB structures interacting with ligand IOI
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q9Y233n/aIOI5sfre5sfrA1A:458-770
Q9Y233n/aIOI5sfre5sfrB1B:457-771
Q9Y233n/aIOI5sfre5sfrC1C:458-770
Q9Y233n/aIOI5sfre5sfrD1D:459-768