DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Ligand Name
2-{2-[3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]ethyl}-1H-isoindole-1,3(2H)-dione
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
ZIRMIZXHXVTMLL-UHFFFAOYSA-N
SMILES
COc1ccc(cc1)N2C(=Nc3ccccc3C2=O)CCN4C(=O)c5ccccc5C4=O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5SGT
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Color Legend
Unassigned regionsLigand / hetero atomse5sgtA1e5sgtB1e5sgtC1e5sgtD1
ECOD domains from experimental PDB structures interacting with ligand IYS
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q9Y233n/aIYS5sgte5sgtA1A:458-770
Q9Y233n/aIYS5sgte5sgtB1B:457-771
Q9Y233n/aIYS5sgte5sgtC1C:458-770
Q9Y233n/aIYS5sgte5sgtD1D:459-768